Profitez de la vie comme si c'est le dernier jour et faites des projets comme si elle était éternelle

Leila TIRICHINE

Directrice de recherche CNRS

section 23
Équipe :

Thèmes de recherche

Mécanismes moléculaires des interactions micro-algues facteurs biotiques et abiotiques de l’environnement, Biotechnologies, Bio-informatique

Projets

Parcours universitaire

2018 – DU bioinformatique Université Paris Diderot

2000 – Doctorat en Biologie Moléculaire et Cellulaire, INP Toulouse

1996 – DEA en génétique Quantitative et Amélioration des Plantes, ENSA Rennes

1995 – Diplôme d’ingénieur Agronome ENSA Toulouse

Publications

5 publications

Chandola, Udita; Trottier, Camille; Gaudin, Marinna; Manirakiza, Erik; Menicot, Samuel; Louvet, Isabelle; Lacour, Thomas; Chaumier, Timothée; Tanaka, Atsuko; Chaffron, Samuel; Tirichine, Leila

Combined in vivo and in situ genome-resolved metagenomics reveals novel symbiotic nitrogen fixing interactions between non-cyanobacterial diazotrophs and microalgae Article de journal À paraître

Dans: bioRxiv, À paraître.

Résumé | Liens | BibTeX

Wu, Yue; Timothée, Chaumier; Manirakiza, Eric; Veluchamy, Alaguraj; Tirichine, Leila

PhaeoEpiView: An epigenome browser of the newly assembled genome of the model diatom Phaeodactylum tricornutum Article de journal À paraître

Dans: bioRxiv, À paraître.

Résumé | Liens | BibTeX

Zhao, Xue; Hoguin, Antoine; Chaumier, Timothée; Tirichine, Leila

Epigenetic Control of Diatom Genomes: An Overview from In Silico Characterization to Functional Studies Chapitre d'ouvrage

Dans: Falciatore, Angela; Mock, Thomas (Ed.): The Molecular Life of Diatoms, p. 179–202, Springer International Publishing, Cham, 2022, ISBN: 978-3-030-92499-7.

Résumé | Liens | BibTeX

Bourdareau, Simon; Godfroy, Olivier; Gueno, Josselin; Scornet, Delphine; Coelho, Susana M.; Tirichine, Leila; Cock, Jean Mark

An Efficient Chromatin Immunoprecipitation Protocol for the Analysis of Histone Modification Distributions in the Brown Alga Ectocarpus Article de journal

Dans: Methods Protoc. , vol. 36, iss. 3, p. 36, 2022.

Liens | BibTeX

Gueno, Josselin; Borg, Michael; Bourdareau, Simon; Cossard, Guillaume; Godfroy, Olivier; Lipinska, Agnieszka; Tirichine, Leila; Cock, J Mark; Coelho, Susana M

Chromatin landscape associated with sexual differentiation in a UV sex determination system Article de journal

Dans: Nucleic Acids Res, vol. 50, iss. 6, p. 3307-3322, 2022, ISSN: 1362-4962.

Résumé | Liens | BibTeX

5 publications

Bourdareau, Simon; Tirichine, Leila; Lombard, Bérangère; Loew, Damarys; Scornet, Delphine; Wu, Yue; Coelho, Susana M; Cock, Mark J

Histone modifications during the life cycle of the brown alga Ectocarpus Article de journal

Dans: Genome Biology, vol. 22, no. 1, 2021, ISSN: 1474760X.

Résumé | Liens | BibTeX

Hoguin, Antoine; Rastogi, Achal; Bowler, Chris; Tirichine, Leila

Genome ‑ wide analysis of allele ‑ specific expression of genes in the model diatom Phaeodactylum tricornutum Article de journal

Dans: Scientific Reports, p. 1–10, 2021, ISSN: 2045-2322.

Résumé | Liens | BibTeX

Hoguin, Antoine; Mohamed, Ouardia Ait; Bowler, Chris; Genovesio, Auguste; Vieira, Fabio Rocha Jimenez; Tirichine, Leila

Evolutionary analysis of DNA methyltransferases in microeukaryotes: Insights from the model diatom Phaeodactylum tricornutum Article de journal

Dans: bioRxiv, 2021.

Résumé | Liens | BibTeX

Zhao, Xue; Rastogi, Achal; Cabanillas, Anne Flore Deton; Mohamed, Ouardia Ait; Cantrel, Catherine; Lombard, Berangère; Murik, Omer; Genovesio, Auguste; Bowler, Chris; Bouyer, Daniel; Loew, Damarys; Lin, Xin; Veluchamy, Alaguraj; Vieira, Fabio Rocha Jimenez; Tirichine, Leila

Genome wide natural variation of H3K27me3 selectively marks genes predicted to be important for cell differentiation in Phaeodactylum tricornutum Article de journal

Dans: New Phytologist, p. nph.17129, 2021, ISSN: 0028-646X.

Résumé | Liens | BibTeX

Armbrecht, Linda; Eisenhofer, Raphael; Utge, José; Sibert, Elizabeth C; Rocha, Fabio; Ward, Ryan; Karlusich, Juan José Pierella; Tirichine, Leila; Norris, Richard; Summers, Mindi; Bowler, Chris

Paleo-diatom composition from Santa Barbara Basin deep-sea sediments: a comparison of 18S-V9 and diat-rbcL metabarcoding vs shotgun metagenomics Article de journal

Dans: ISME Communications, vol. 1, no. 1, p. 1–10, 2021.

BibTeX

5 publications

Ait-Mohamed, Ouardia; Vanclová, Anna M G Novák; Joli, Nathalie; Liang, Yue; Zhao, Xue; Genovesio, Auguste; Tirichine, Leila; Bowler, Chris; Dorrell, Richard G

PhaeoNet: A Holistic RNAseq-Based Portrait of Transcriptional Coordination in the Model Diatom Phaeodactylum tricornutum Article de journal

Dans: Frontiers in Plant Science, vol. 11, 2020, ISSN: 1664462X.

Résumé | Liens | BibTeX

Zhao, Xue; Hoguin, Antoine; Chaumier, Timothée; Tirichine, Leila

Epigenetic control of diatom genomes: An overview from in Silico characterisation to functional studies Chapitre d'ouvrage

Dans: The molecular life of diatoms, Springer Nature Switzerland AG, 2020.

BibTeX

Sato, Shinya; Nanjappa, Deepak; Dorrell, Richard G; Vieira, Fabio Rocha Jimenez; Kazamia, Elena; Tirichine, Leila; Veluchamy, Alaguraj; Heilig, Roland; Aury, Jean Marc; Jaillon, Olivier; Wincker, Patrick; Fussy, Zoltan; Obornik, Miroslav; Muñoz-Gómez, Sergio A; Mann, David G; Bowler, Chris; Zingone, Adriana

Genome-enabled phylogenetic and functional reconstruction of an araphid pennate diatom Plagiostriata sp. CCMP470, previously assigned as a radial centric diatom, and its bacterial commensal Article de journal

Dans: Scientific Reports, vol. 10, no. 1, p. 1–12, 2020, ISSN: 20452322.

Résumé | Liens | BibTeX

Fan, Xiao; Han, Wentao; Teng, Linhong; Jiang, Peng; Zhang, Xiaowen; Xu, Dong; Li, Chang; Pellegrini, Matteo; Wu, Chunhui; Wang, Yitao; Kaczurowski, Michelle Joyce Slade; Lin, Xin; Tirichine, Leila; Mock, Thomas; Ye, Naihao

Single-base methylome profiling of the giant kelp Saccharina japonica reveals significant differences in DNA methylation to microalgae and plants Article de journal

Dans: New Phytologist, vol. 225, no. 1, p. 234–249, 2020, ISSN: 14698137.

Résumé | Liens | BibTeX

Zhao, Xue; Cabanillas, Anne Flore Deton; Veluchamy, Alaguraj; Bowler, Chris; Vieira, Fabio Rocha Jimenez; Tirichine, Leila

Probing the Diversity of Polycomb and Trithorax Proteins in Cultured and Environmentally Sampled Microalgae Article de journal

Dans: Frontiers in Marine Science, vol. 7, p. 189, 2020, ISSN: 2296-7745.

Résumé | Liens | BibTeX

4 publications

Murik, Omer; Tirichine, Leila; Prihoda, Judit; Thomas, Yann; Araújo, Wagner L; Allen, Andrew E; Fernie, Alisdair R; Bowler, Chris

Downregulation of mitochondrial alternative oxidase affects chloroplast function, redox status and stress response in a marine diatom Article de journal

Dans: New Phytologist, vol. 221, no. 3, p. 1303–1316, 2019, ISSN: 14698137.

Résumé | Liens | BibTeX

Huang, Ruiping; Ding, Jiancheng; Gao, Kunshan; de Carvalho, Maria Helena; Tirichine, Leila; Bowler, Chris; Lin, Xin

A Potential Role for Epigenetic Processes in the Acclimation Response to Elevated pCO2 in the Model Diatom Phaeodactylum tricornutum Article de journal

Dans: Frontiers in Microbiology, vol. 9, p. 3342, 2019, ISSN: 1664-302X.

Résumé | Liens | BibTeX

Shao, Zhanru; Thomas, Yann; Hembach, Lea; Xing, Xiaohui; Duan, Delin; Moerschbacher, Bruno M; Bulone, Vincent; Tirichine, Leila; Bowler, Chris

Comparative characterization of putative chitin deacetylases from Phaeodactylum tricornutum and Thalassiosira pseudonana highlights the potential for distinct chitin-based metabolic processes in diatoms Article de journal

Dans: New Phytologist, vol. 221, no. 4, p. 1890–1905, 2019, ISSN: 14698137.

Résumé | Liens | BibTeX

Caputi, L; Carradec, Q; Eveillard, D; Kirilovsky, A; Pelletier, E; Karlusich, J J Pierella; Vieira, F Rocha Jimenez; Villar, E; Chaffron, S; Malviya, S; Scalco, E; Acinas, S G; Alberti, A; Aury, J -M; Benoiston, A -S; Bertrand, A; Biard, T; Bittner, L; Boccara, M; Brum, J R; Brunet, C; Busseni, G; Carratalà, A; Claustre, H; Coelho, L P; Colin, S; Daniello, S; Silva, C Da; Core, M Del; Doré, H; Gasparini, S; Kokoszka, F; Jamet, J -L; Lejeusne, C; Lepoivre, C; Lescot, M; Lima-Mendez, G; Lombard, F; Lukeš, J; Maillet, N; Madoui, M -A; Martinez, E; Mazzocchi, M G; Néou, M B; Paz-Yepes, J; Poulain, J; Ramondenc, S; Romagnan, J -B; Roux, S; Manta, D Salvagio; Sanges, R; Speich, S; Sprovieri, M; Sunagawa, S; Taillandier, V; Tanaka, A; Tirichine, Leila; Trottier, Camille; Uitz, J; Veluchamy, A; Veselá, J; Vincent, F; Yau, S; Kandels-Lewis, S; Searson, S; Dimier, C; Picheral, M; Bork, P; Boss, E; de Vargas, C; Follows, M J; Grimsley, N; Guidi, L; Hingamp, P; Karsenti, E; Sordino, P; Stemmann, L; Sullivan, M B; Tagliabue, A; Zingone, A; Garczarek, L; DÓrtenzio, F; Testor, P; Not, F; DÁlcalà, M R; Wincker, P; Bowler, C; Iudicone, D

Community-Level Responses to Iron Availability in Open Ocean Plankton Ecosystems Article de journal

Dans: Global Biogeochemical Cycles, vol. 33, no. 3, 2019, ISSN: 19449224.

Résumé | Liens | BibTeX

2018

Nomaguchi, Tatsuhiro; Maeda, Yoshiaki; Yoshino, Tomoko; Asahi, Toru; Tirichine, Leila; Bowler, Chris; Tanaka, Tsuyoshi

Homoeolog expression bias in allopolyploid oleaginous marine diatom Fistulifera solaris Article de journal

Dans: BMC Genomics, vol. 19, no. 1, 2018.

Liens | BibTeX

Rastogi, Achal; Maheswari, Uma; Dorrell, Richard G; Vieira, Fabio Rocha Jimenez; Maumus, Florian; Kustka, Adam; McCarthy, James; Allen, Andy E; Kersey, Paul; Bowler, Chris; Tirichine, Leila

Integrative analysis of large scale transcriptome data draws a comprehensive landscape of Phaeodactylum tricornutum, genome and evolutionary origin of diatoms Article de journal

Dans: Scientific Reports, vol. 8, no. 1, 2018.

Liens | BibTeX

Carradec, Quentin; Eric,; Pelletier,; Silva, Corinne Da; Alberti, Adriana; Seeleuthner, Yoann; Blanc-Mathieu, Romain; Lima-Mendez, Gipsi; Rocha, Fabio; Tirichine, Leila; Labadie, Karine; Kirilovsky, Amos; Bertrand, Alexis; Engelen, Stefan; Madoui, Mohammed-Amin; Méheust, Raphaël; Poulain, Julie; Romac, Sarah; Richter, Daniel J; Yoshikawa, Genki; Dimier, Céline; Kandels-Lewis, Stefanie; Picheral, Marc; Searson, Sarah; Jaillon, Olivier; Aury, Jean-Marc; Karsenti, Eric; Sullivan, Matthew B; Sunagawa, Shinichi; Bork, Peer; Not, Fabrice; Hingamp, Pascal; Raes, Jeroen; Guidi, Lionel; Ogata, Hiroyuki; de Vargas, Colomban; Iudicone, Daniele; Bowler, Chris; Wincker, Patrick

A global ocean atlas of eukaryotic genes Article de journal

Dans: Nature Communications, vol. 9, no. 1, 2018.

Liens | BibTeX

2017

Tirichine, Leila; Rastogi, Achal; Bowler, Chris

Recent progress in diatom genomics and epigenomics Article de journal

Dans: Current Opinion in Plant Biology, vol. 36, p. 46 - 55, 2017, ISSN: 1369-5266.

Résumé | Liens | BibTeX

2016

Rastogi, Achal; Murik, Omer; Bowler, Chris; Tirichine, Leila

PhytoCRISP-Ex: a web-based and stand-alone application to find specific target sequences for CRISPR/CAS editing Article de journal

Dans: BMC Bioinformatics, vol. 17, no. 1, 2016.

Liens | BibTeX

2015

Veluchamy, Alaguraj; Rastogi, Achal; Lin, Xin; Lombard, Bérangère; Murik, Omer; Thomas, Yann; Dingli, Florent; Rivarola, Maximo; Ott, Sandra; Liu, Xinyue; Sun, Yezhou; Rabinowicz, Pablo D; McCarthy, James; Allen, Andrew E; Loew, Damarys; Bowler, Chris; Tirichine, Leila

An integrative analysis of post-translational histone modifications in the marine diatom Phaeodactylum tricornutum, Article de journal

Dans: Genome Biology, vol. 16, no. 1, 2015.

Liens | BibTeX

Morrissey, Joe; Sutak, Robert; Paz-Yepes, Javier; Tanaka, Atsuko; Moustafa, Ahmed; Veluchamy, Alaguraj; Thomas, Yann; Botebol, Hugo; Bouget, François-Yves; McQuaid, Jeffrey B.; Tirichine, Leila; Allen, Andrew E.; Lesuisse, Emmanuel; Bowler, Chris

A Novel Protein, Ubiquitous in Marine Phytoplankton, Concentrates Iron at the Cell Surface and Facilitates Uptake Article de journal

Dans: Current Biology, vol. 25, no. 3, p. 364–371, 2015.

Liens | BibTeX

Tanaka, Atsuko; Martino, Alessandra De; Amato, Alberto; Montsant, Anton; Mathieu, Benjamin; Rostaing, Philippe; Tirichine, Leila; Bowler, Chris

Ultrastructure and Membrane Traffic During Cell Division in the Marine Pennate Diatom Phaeodactylum tricornutum, Article de journal

Dans: Protist, vol. 166, no. 5, p. 506 - 521, 2015, ISSN: 1434-4610.

Résumé | Liens | BibTeX

Abida, Heni; Dolch, Lina-Juana; Meï, Coline; Villanova, Valeria; Conte, Melissa; Block, Maryse A; Finazzi, Giovanni; Bastien, Olivier; Tirichine, Leila; Bowler, Chris; Rébeillé, Fabrice; Petroutsos, Dimitris; Jouhet, Juliette; Maréchal, Eric

Membrane Glycerolipid Remodeling Triggered by Nitrogen and Phosphorus Starvation in Phaeodactylum tricornutum, Article de journal

Dans: Plant Physiology, vol. 167, no. 1, p. 118–136, 2015, ISSN: 0032-0889.

Résumé | Liens | BibTeX

Stagiaires encadrés :

  • Chaima NACIRI , spécialisation Transition Environnementale et Durabilité, Ecole Supérieure d'Agriculture d'Angers
  • Maina BON , Ingénieur Horticulture et Paysage, Institut Agro Rennes-Angers
  • Clément POULAIN , Polytech Nantes, Nantes Université
  • Clara GUILLOUCHE , Licence Sciences de la Vie parcours BCM option ABT, Nantes Université
  • Nikunj SHARMA , doctorant en échange, Université du Québec à Trois-Rivières
  • Irene ROMERO RODRIGUEZ , M1 Microbiologie Fondamentale et Appliquée, Université de Bretagne Occidentale

Liens